Early detection of myocardial infarction (MI), a critical condition arising from coronary artery disease (CAD), is vital to prevent further myocardial damage. This study introduces a novel method for early MI detection using a one-class classification (OCC) algorithm in echocardiography. Our study overcomes the challenge of limited echocardiography data availability by adopting a novel approach based on Multi-modal Subspace Support Vector Data Description. The proposed technique involves a specialized MI detection framework employing multi-view echocardiography incorporating a composite kernel in the non-linear projection trick, fusing Gaussian and Laplacian sigmoid functions. Additionally, we enhance the update strategy of the projection matrices by adapting maximization for both or one of the modalities in the optimization process. Our method boosts MI detection capability by efficiently transforming features extracted from echocardiography data into an optimized lower-dimensional subspace. The OCC model trained specifically on target class instances from the comprehensive HMC-QU dataset that includes multiple echocardiography views indicates a marked improvement in MI detection accuracy. Our findings reveal that our proposed multi-view approach achieves a geometric mean of 71.24\%, signifying a substantial advancement in echocardiography-based MI diagnosis and offering more precise and efficient diagnostic tools.

Myocardial infarction (MI) is a severe case of coronary artery disease (CAD) and ultimately, its detection is substantial to prevent progressive damage to the myocardium. In this study, we propose a novel view-fusion model named self-attention fusion network (SAF-Net) to detect MI from multi-view echocardiography recordings. The proposed framework utilizes apical 2-chamber (A2C) and apical 4-chamber (A4C) view echocardiography recordings for classification. Three reference frames are extracted from each recording of both views and deployed pre-trained deep networks to extract highly representative features. The SAF-Net model utilizes a self-attention mechanism to learn dependencies in extracted feature vectors. The proposed model is computationally efficient thanks to its compact architecture having three main parts: a feature embedding to reduce dimensionality, self-attention for view-pooling, and dense layers for the classification. Experimental evaluation is performed using the HMC-QU-TAU dataset which consists of 160 patients with A2C and A4C view echocardiography recordings. The proposed SAF-Net model achieves a high-performance level with 88.26% precision, 77.64% sensitivity, and 78.13% accuracy. The results demonstrate that the SAF-Net model achieves the most accurate MI detection over multi-view echocardiography recordings.

Myocardial infarction (MI) is the leading cause of mortality in the world that occurs due to a blockage of the coronary arteries feeding the myocardium. An early diagnosis of MI and its localization can mitigate the extent of myocardial damage by facilitating early therapeutic interventions. Following the blockage of a coronary artery, the regional wall motion abnormality (RWMA) of the ischemic myocardial segments is the earliest change to set in. Echocardiography is the fundamental tool to assess any RWMA. Assessing the motion of the left ventricle (LV) wall only from a single echocardiography view may lead to missing the diagnosis of MI as the RWMA may not be visible on that specific view. Therefore, in this study, we propose to fuse apical 4-chamber (A4C) and apical 2-chamber (A2C) views in which a total of 11 myocardial segments can be analyzed for MI detection. The proposed method first estimates the motion of the LV wall by Active Polynomials (APs), which extract and track the endocardial boundary to compute myocardial segment displacements. The features are extracted from the A4C and A2C view displacements, which are fused and fed into the classifiers to detect MI. The main contributions of this study are 1) creation of a new benchmark dataset by including both A4C and A2C views in a total of 260 echocardiography recordings, which is publicly shared with the research community, 2) improving the performance of the prior work of threshold-based APs by a Machine Learning based approach, and 3) a pioneer MI detection approach via multi-view echocardiography by fusing the information of A4C and A2C views. Experimental results show that the proposed method achieves 90.91% sensitivity and 86.36% precision for MI detection over multi-view echocardiography.